PHCL4021

Cancer is a major health problem that affects millions. PHCL 4021 (formerly PHCL 4020) will provide students with a strong foundation in the pharmacological principles of anti-cancer therapies by examining the mechanisms of drug action on the cellular and molecular biology of cancer. Lectures will cover how major classes of anti-cancer drugs target key cancer hallmarks, including growth regulation, cell death, metabolism, genome stability, signaling pathways, and metastasis. Drug modalities from small molecules to advanced biologics will be discussed. The course will focus on understanding the molecular mechanisms underlying the efficacy, side effects, and limitations of these therapies, and how these factors shape the development of new treatment strategies. Students will also explore emerging areas of cancer therapy through reading recent research studies and working with peers on a group project, with continual guidance and feedback from the instructors. Additionally, the course will cover the drug discovery and development process for anti-cancer drugs. Upon completing the course, students will have a comprehensive understanding of current cancer therapies and a solid foundation of knowledge to further explore the development of novel cancer therapeutics. PHCL 4021 is the new course number for the former PHCL 4020.

Every Fall